Skip to main content
. 2016 Dec 24;8(7):11555–11565. doi: 10.18632/oncotarget.14135

Figure 4. Dex-induced KLF5 contributes to Dex-mediated drug resistance.

Figure 4

A &B. DTX/Cpt-suppressed TNBC cells viability was partially rescued by Dex treatment. Suppression of KLF5 or GR by siRNA or MIF blocked the cell viability increase induced by Dex. C-F. DTX/Cpt-suppressed KLF5 expression and induced apoptosis in TNBC cells were partially rescued by Dex treatment. Inhibition of either KLF5 or GR by siRNA or MIF abolished the effect of Dex. *, P<0.05; **, P<0.01; ***, P<0.001.