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A-C. KLF5 depletion blocked Dex-induced DTX resistance in vivo. 1 × 106 HCC1806 control or KLF5 depleted cellswere injected to female nude mice subcutaneously. When the tumor size reached around 70 mm3, mice were treated with injected with 10 mg/kg DTX with or without 1mg/ml Dex. D. DTX or Dex treatment does not significantly affect body weight of nude mice.
