Table 3. Effects of matrine on intestinal chemokine receptors in mice.
| Item | Control | 1 mg/kg Matrine | 5 mg/kg Matrine | 10 mg/kg Matrine |
|---|---|---|---|---|
| Jejunum | ||||
| CCR2 | 1.00 ± 0.13 | 1.21 ± 0.16 | 1.26 ± 0.13 | 1.32 ± 0.12 |
| CCR5 | 1.00 ± 0.11b | 1.09 ± 0.11b | 1.17 ± 0.12b | 1.43 ± 0.14a |
| CCR6 | 1.00 ± 0.07b | 1.09 ± 0.16b | 1.14 ± 0.13b | 1.75 ± 0.18a |
| CCR7 | 1.00 ± 0.15b | 1.17 ± 0.13b | 1.65 ± 0.11a | 1.88 ± 0.21a |
| CCR8 | 1.00 ± 0.09 | 1.12 ± 0.16 | 1.35 ± 0.25 | 1.43 ± 0.24 |
| Ileum | ||||
| CCR2 | 1.00 ± 0.07b | 1.16 ± 0.17b | 1.18 ± 0.14b | 1.73 ± 0.07a |
| CCR5 | 1.00 ± 0.17b | 1.19 ± 0.12ab | 1.25 ± 0.17ab | 1.43 ± 0.14a |
| CCR6 | 1.00 ± 0.05 | 1.19 ± 0.19 | 1.93 ± 0.19 | 1.06 ± 0.14 |
| CCR7 | 1.00 ± 0.08b | 1.43 ± 0.13a | 1.77 ± 0.18a | 2.01 ± 0.25a |
| CCR8 | 1.00 ± 0.14 | 1.15 ± 0.16 | 1.21 ± 0.14 | 1.38 ± 0.28 |
Data are expressed as the mean ± standard error of the mean. Values in the same row with different superscripts are significant (P < 0.05), while values with same superscripts are not significant different (P > 0.05).