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. 2016 Dec 28;8(7):11729–11738. doi: 10.18632/oncotarget.14329

Figure 4. YF-18 treatment leads to Skp2 down-regulation and its targets p27 and E-cadherin up-regulation.

Figure 4

A. P27 and E-cadherin were up-regulated upon YF-18 treatment. B. YF-18 reduced Skp2 expression in a time- and dose-dependent manner. C. Treatment with YF-18 led to transcription inhibition of Skp2. Data is represented as mean ± SD.