Table 3. EGLN1/PHD2 D4E rs186996510 genotype and the risk of lung cancer in Nepal.
| Patients | Controls | OR* | OR** | OR*** | |||
|---|---|---|---|---|---|---|---|
| Wildtype | Carrier | Wildtype | Carrier | OR(95%CI) | OR(95%CI) | OR(95%CI) | |
| Hetero/Homozygote | 174 | 40 | 192 | 21 | 2.35 (1.31-4.22) | 2.26 (1.27-4.02) | 2.04 (1.13-3.71) |
| By sex | |||||||
| Men | 94 | 20 | 121 | 8 | 2.35 (1.31-4.22) | 3.49 (1.45-8.42) | 3.34 (1.36-8.23) |
| Women | 80 | 20 | 71 | 13 | 4.98 (1.8-13.74) | 1.46 (0.67-3.17) | 1.11 (0.48-2.55) |
| By smoking status | |||||||
| Never smoker | 18 | 4 | 71 | 7 | 2.25 (1.13-4.48) | 2.24 (0.58-8.67) | |
| Ever smoker | 156 | 36 | 121 | 14 | 1.33 (0.61-2.89) | 2.15 (1.1-4.22) | |
| By age | |||||||
| Less than 60 years | 66 | 12 | 116 | 9 | 2.56 (0.65-10.03) | 2.43 (0.96-6.14) | 2.46 (0.94-6.39) |
| 60+ years | 108 | 28 | 76 | 12 | 2.48 (0.98-6.28) | 1.81 (0.85-3.86) | 1.6 (0.74-3.44) |
| By residential area | |||||||
| Plain | 97 | 14 | 139 | 13 | 3.31 (1.19-9.19) | 1.58 (0.71-3.52) | 1.46 (0.63-3.37) |
| Hills, mountains | 77 | 26 | 53 | 8 | 1.92 (0.88-4.2) | 2.72 (1.09-6.82) | 2.31 (0.94-5.67) |
| By resident | |||||||
| West | 102 | 32 | 87 | 7 | 4.5 (1.8-11.26) | 4.19 (1.73-10.15) | 4.24 (1.69-10.63) |
| East | 72 | 8 | 105 | 14 | 1.58 (0.71-3.51) | 0.87 (0.35-2.21) | 0.75 (0.29-1.93) |
| By religion | |||||||
| Hindu | 162 | 36 | 174 | 14 | 2.77 (1.44-5.32) | 2.68 (1.35-5.34) | |
| Not-Hindu | 12 | 4 | 18 | 7 | 1.44 (0.27-7.83) | 0.83 (0.2-3.56) | |
*
adjusting for Tibetan ethnicity
**
adjusting for Hindu religion
***
adjusting for smoking status