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. 2016 Dec 29;8(7):11788–11796. doi: 10.18632/oncotarget.14352

Table 2. Main results of meta-analysis for colorectal cancer.

Variables No. of studies Effects model HR (95%CI) p Heterogeneity
I2(%) Ph
OS 8 Random 1.28(0.86-1.91) 0.22 75.7 <0.001
Location
Western countries 5 Random 1.11(0.61-2.03) 0.734 82.5 <0.001
Eastern countries 3 Random 1.86(0.83-4.17) 0.132 66.1 0.053
Cancer type
CRC 6 Random 1.2(0.76-1.88) 0.44 80.5 <0.001
RC 2 Random 2.06(0.53-7.96) 0.294 63.8 0.097
Treatment
Surgical resection 7 Random 1.31(0.83-2.06) 0.244 79.2 <0.001
Chemoradiotherapy 1 - 1.21(0.63-2.33) 0.568 - -
DFS 4 Random 1.71(0.78-3.72) 0.179 61.8 0.049
Location
Western countries 1 - 0.87(0.24-3.12) 0.831 - -
Eastern countries 3 Random 2.16(0.75-6.18) 0.152 73.5 0.023
Cancer type
CRC 1 - 1.12(0.86-1.46) 0.414 - -
RC 3 Fixed 2.47(1.21-5.05) 0.013 46.4 0.155
Treatment
Surgical resection 3 Fixed 1.13(0.87-1.46) 0.364 0 0.476
Chemoradiotherapy 1 4.01(1.55-10.37) 0.004 - -