Table 1. Characteristics and risk factors of C. difficile colonization in 205 CRC patients.

Characteristic	No.(%) of patients for C. difficile status		Results for analysis
	C. difficile positive	C. difficile negative	Bivariant		Multivariant logistic
	(n=33)	(n=172)	P value	OR	95% CI	P value
Age	<60 (n=74)	9 (12.2)	65 (87.8)	0.249	1.560	0.652-3.735	0.318
	≥60 (n=131)	24 (18.3)	107 (81.7)
Site	Colon (n=91)	15 (16.5)	76 (83.5)	0.893	0.991	0.397-2.474	0.984
	Rectum (n=114)	18 (15.8)	96 (84.2)
Morphology	Ulcerative (n=134)	25 (18.7)	109 (81.3)	0.171	0.744	0.287-1.926	0.242
	Exophytic (n=71)	8 (11.3)	63 (88.7)
Differentiation	Poor (n=62)	8 (12.9)	54 (87.1)	0.413	1.424	0.825-6.481	0.401
	Well (n=143)	25 (17.5)	118 (82.5)
T stage	Non-T4 (n=150)	20 (13.3)	130 (86.7)	0.075	2.301	0.963-5.500	0.061
	T4 (n=55)	13 (23.6)	42 (76.4)
N stage	LN neg. (n=111)	12 (10.8)	99 (89.2)	0.025*	2.314	1.023-5.235	0.044*
	LN pos. (n=94)	21 (22.3)	73 (77.7)
Albumin (g/L)	<35 (n=17)	5 (29.4)	12 (70.6)	0.119	0.315	0.073-1.357	0.121
	≥35 (n=188)	28 (14.9)	160 (85.1)
FBG (mmol/L)	<7.0 (n=192)	32 (16.7)	160 (83.3)	0.394	0.337	0.033-3.455	0.360
	≥7.0 (n=13)	1 (7.7)	12 (92.3)
BMI	<24 (n=114)	17 (14.9)	97 (85.1)	0.605	1.358	0.581-3.177	0.480
	≥24 (n=91)	16 (17.6)	75 (82.4)
TG (mmol/L)	≥1.70 (n=38)	6 (15.8)	32 (84.2)	0.954	1.129	0.497-4.703	0.917
	<1.70 (n=167)	27 (16.2)	140 (83.8)
TC (mmol/L)	<5.70 (n=190)	31 (16.3)	159 (83.7)	0.762	0.858	0.097-3.199	0.612
	≥5.70 (n=15)	2 (13.3)	13 (86.7)
HDL (mmol/L)	< 0.80 (n=20)	2 (10.0)	18 (90.0)	0.435	1.768	0.337-9.274	0.500
	≥ 0.80 (n=185)	31 (16.8)	154 (83.2)
Hemoglobin (g/L)	<120 (n=55)	10 (18.2)	45 (81.8)	0.623	0.911	0.319-2.602	0.861
	≥120 (n=150)	23 (15.3)	127 (84.7)
OB	Negative (n=75)	18 (24.0)	57 (76.0)	0.019*	0.300	0.131-0.685	0.004*
	Positive (n=130)	15 (11.5)	115 (88.5)

Abbreviations: *P <0.05; LN: Lymph nodes; FBG: Fast blood glucose; BMI: Body mass index; TG: Triglyceride; TC: Total cholesterol; HDL: High density lipoprotein