Table 2. Antibiotic resistance profile of 33 C. difficile strains according to pathology and demographic characteristics.
Antibiotic | No. (%) resistant | ||||||
---|---|---|---|---|---|---|---|
Cancer site | Age | ||||||
Total | Rectum | Colon | P value | <60 | ≥60 | P value | |
n=33 | n=18 | n=15 | n=9 | n=24 | |||
Fusidic acid | 17 (51.5) | 13 (72.2) | 4 (26.7) | 0.01* | 4 (44.4) | 13 (54.2) | 0.62 |
Ciprofloxacin | 26 (78.8) | 14 (77.8) | 12 (80.0) | 0.88 | 9 (100.0) | 17 (70.8) | 0.07 |
Piperacillin/Tazobactam | 1 (3.0) | 1 (5.6) | 0 (0) | NA | 0 (0) | 1 (4.2) | NA |
Metronidazole | 0 (0) | 0 (0) | 0 (0) | NA | 0 (0) | 0 (0) | NA |
Rifampicin | 9 (27.3) | 5 (27.8) | 4 (26.7) | 0.94 | 1 (11.1) | 8 (33.3) | 0.20 |
Moxifloxacin | 15 (45.5) | 6 (33.3) | 9 (60.0) | 0.13 | 7 (77.8) | 8 (33.3) | 0.02* |
Gatifloxacin | 14 (42.4) | 8 (44.4) | 6 (40.0) | 0.80 | 2 (22.2) | 12 (50.0) | 0.15 |
Vancomycin | 0 (0) | 0 (0) | 0 (0) | NA | 0 (0) | 0 (0) | NA |
Clindamycin | 21 (63.6) | 12 (66.7) | 9 (60.0) | 0.69 | 6 (66.7) | 15 (62.5) | 0.83 |
Levofloxacin | 22 (66.7) | 12 (66.7) | 10 (66.7) | 1.00 | 7 (77.8) | 15 (62.5) | 0.41 |
Tetracycline | 16 (48.5) | 8 (44.4) | 8 (53.3) | 0.53 | 6 (66.7) | 10 (41.7) | 0.20 |
Erythromycin | 21 (63.6) | 11 (61.1) | 10 (66.7) | 0.74 | 8 (88.9) | 13 (54.2) | 0.07 |
*P <0.05