Table 4. Comparison of sensitivity between CEA and cfDNA LHI for CRC patients.
All stage (n = 114) | Stage I/II (n = 57) | Stage III/IV (n= 57) | |
---|---|---|---|
CEA (≥5.0 ng/mL) | |||
Sensitivity | 54.4% (62/114) | 40.4% (23/57) | 68.4% (39/57) |
cfDNA LHI | |||
Sensitivity | 65.8% (75/114) | 63.2% (36/57) | 68.4% (39/57) |
Abbreviations: cfDNA, circulating cell-free DNA; LHI, LINE-1 hypomethylation index; CRC, colorectal cancer; CEA, carcinoembryonic antigen.