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. 2017 Jan 3;8(7):11990–12002. doi: 10.18632/oncotarget.14467

Figure 7. The efficacy of Apatinib on suppressing GC growth in xenograft tumor models.

Figure 7

A. In nude mouse xenografts of gastric cancer cells that overexpressed VEGFR2 and VEGF, Apatinib delays tumor growth. B. Apatinib decreased tumor volume in SGC-7901 and BGC-823 tumor models, but not in the MGC-803 model when mice were sacrificed. C. Apatinib-treated tumors decreased total tumor weights in SGC-7901 and BGC-823 tumor models, but not in the MGC-803 tumor model. D. Measured by IHC, Apatinib decreased the Ki67 positive rate of tumor cells in SGC-7901 and BGC-823 tumor models, but not in the MGC-803 tumor model. Mean±SEM, t-test, *P<0.05, **P<0.01, ***P<0.001.