Figure 6. NMI induced MAPK/ERK signaling pathway.
A. Western blotting showed the ERK1/2 and phospho-ERK1/2 expressions in HCC-LM3 cells transfected with shNMI or Huh7 cells with up-regulation of NMI and their corresponding controls respectively. B. The expressions of phosphorylated EKR1/2 were decreased in subcutaneous tumors of mice models implanted with NMI knockdown HCC-LM3 cells compared with those of controls.