Table 5. LncRNAs associated with stemness mantenance in CRC.

lncRNA	In colorectal cancer, its expressions is:	Functions	Reference
LncRNA-HIF2PUT	Upregulated	Enhances the HIF-2α expression and promotes CSC properties.	[48]
LncRNA HOTAIR	Upregulated	Promotes CSC properties, increases cellular proliferation, migration, invasion, colony-forming.	[49]
Lnc34a(locus mainly in the nucleus)	Upregulated	Enhances CSC self-renewal and tumorigenesis and suppresses miR-34a expression.	[50]
LincRNA-p21	Downregulated	Attenuates the viability, self-renewal, and glycolysis of CSCs.	[51]