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. 2017 Mar 17;12:200. doi: 10.1186/s11671-017-1982-3

Fig. 1.

Fig. 1

Production of ECM molecules by fibroblasts decreased on exposure to AgNPs. The human fibroblast cell line treated with AgNPs at concentrations of 0.1, 1, or 10 μg/mL for 24 h was analysed using indirect immunofluorescence to detect laminin and collagen-1 production. Photomicrographs in (a) show laminin (green; upper panels) and collagen-1 (green; lower panels) production in NP-treated cells. Magnification, 200×. Graphs in b and c show the fluorescence intensity for laminin and collagen-1, respectively. Data have been presented as mean ± SEM. CTR: non-treated cells; *p < 0.05, **p < 0.01, ***p < 0.001