Table 2.
Proteins associated with siderophore biosynthesis and transporter activity with increased abundance in A. fumigatus ΔmirC mycelia grown for 72 h in iron-deplete MM compared to A. fumigatus WT (See also Tables S3, S6, S7, S10 and S11).
| Protein description | Log2 (Fold Increase) | p-value | Peptides | Sequence coverage [%] | Protein IDs |
|---|---|---|---|---|---|
| Ortholog(s) have iron ion transmembrane transporter activity | Unique | N/A | 4 | 33.7 | AFUA_6G12550 |
| Ortholog(s) have guanine nucleotide transmembrane transporter activity, role in cellular iron ion homeostasis | 1.54 | 5.53E-04 | 17 | 56.6 | AFUA_1G07450 |
| L-ornithine N5-oxygenase, first committed step in siderophore biosynthesis. SidA. | 1.47 | 4.72E-06 | 48 | 83.2 | AFUA_2G07680 |
| Cytochrome c; transcript derepressed during iron starvation in hapX mutant | 1.02 | 6.79E-03 | 5 | 14 | AFUA_2G13110 |
| Putative peroxisome biogenesis factor | 1.32 | 1.70E-03 | 5 | 26.8 | AFUA_6G07740 |
| Putative peroxin with a predicted role in peroxisome biogenesis | 1.14 | 4.34E-03 | 3 | 12 | AFUA_2G17100 |
| Putative long-chain-fatty-acid-CoA ligase. SidI. | 1.09 | 5.69E-04 | 38 | 75.8 | AFUA_1G17190 |