Fig. 1.

Effect of the GSDMB rs8067378 polymorphism on GSDMB1–4 isoform transcript levels in cancerous cervical tissues (a) and non-cancerous tissues (b). Frozen tissue was homogenized, followed by total RNA isolation. Quantitative analyses of GSDMB transcript levels were performed by quantitative real-time polymerase chain reaction using the SYBR Green I system. The quantity of GSDMB transcript levels in each sample was standardized by the geometric mean of references using hydroxymethylbilane synthase and β-2-microglobulin cDNA levels. Kruskal–Wallis test with ^aDunn’s post-hoc or ^bTukey’s post-hoc test. GSDMB gasdermin B