Table 3.

The distribution of rs8067378 genotypes among squamous cell carcinoma risks: parity, oral contraceptive use, tobacco smoking, and menopausal status

High risk exposure	Patients		Controls		Adjusted odds ratio (95% CI)	p value	Adjusted odds ratio (95% CI)	p value
Genotype	Ever	Never	Ever	Never	Ever		Never
Parity
A/A	79	12	112	15	Referent		Referent
G/A	228	29	241	35	1.347 (0.956–1.897)	0.0881	1.129 (0.443–2.878)	0.7954
G/G	121	17	95	13	1.323 (1.083–1.615)	0.0059	1.289 (0.752–2.209)	0.3447
G/A + G/G	349	46	336	48	1.484 (1.071–2.055)	0.0174	1.274 (0.526–3.085)	0.5876
Oral contraceptive use
A/A	41	50	56	71	Referent		Referent
G/A	116	141	119	157	1.558 (0.944–2.573)	0.0818	1.314 (0.853–2.024)	0.2145
G/G	66	72	47	61	1.376 (1.043–1.816)	0.0232	1.278 (0.991–1.648)	0.0571
G/A + G/G	182	213	166	218	1.589 (1.001–2.523)	0.0509	1.407 (0.934–2.121)	0.1018
Smoking
A/A	28	63	43	84	Referent		Referent
G/A	90	167	94	182	1.667 ().933–2.976)	0.0829	1.220 (0.826–1.803)	0.3169
G/G	59	79	37	71	1.666 (1.195–2.322)	0.0024	1.196 (0.948–1.508)	0.1288
G/A + G/G	149	246	131	253	1.958 (1.133–3.384)	0.0157	1.306 (0.900–1.896)	0.1586
Menopausal status
	Premenopausal	Postmenopausal	Premenopausal	Postmenopausal	Premenopausal		Postmenopausal
A/A	27	64	47	80	Referent		Referent
G/A	105	152	108	168	1.739 (1.000–3.023)	0.0501	1.197 (0.800–1.791)	0.3796
G/G	39	99	42	66	1.381 (0.981–1.939)	0.0606	1.334 (1.059–1.679)	0.0138
G/A + G/G	144	251	150	234	1.662 (0.977–2.826)	0.0602	1.367 (0.938–1.992)	0.1035

CI confidence interval

All p values were adjusted by age. Significant results are highlighted in bold font