Figure 5.

Cytotoxicity of 5-FU and 5-FU-PLGA NPs in HCT 116 and HT-29 cells. Cells were exposed to 100 μM (black bars) or 250 μM (gray bars) of 5-FU and 5-FU-PLGA NPs. At the end of the exposure, MTT cell viability was determined as described in materials and methods. (A) HCT 116 cells and (B) HT-29 cells. Data represented are mean ± SD of three identical experiments made in three replicate. ^*Significant difference between 5-FU and 5-FU-PLGA NPs exposure (p < 0.05 for each).