Figure 1.

Expression of Oligoendroglial Markers in EYFP+ Cells of the SEZ and CC

(A–H) At 4 days post tamoxifen, expression of EYFP was induced within the SEZ, in GFAP+ astrocytes, and in scattered ependymal cells, arrows and arrowheads, respectively, in (A), but no co-expression with Olig2 was detected (B): yellow arrows indicate OLIG2+ cells in the SEZ, white arrow an OLIG2+ cell in the striatum. At 15 days, double EYFP+/PDGFRα+ cells were detected in the SEZ (C), white arrow. The majority of EYFP+ cells in the CC co-expressed GFAP (D). At 1 month, in the CC EYFP+/GFAP− cells were detected, yellow arrowheads in (E), near EYFP+/GFAP+ astrocytes (white arrows). EYFP+ oligodendrocytes are indicated by the star in (F) (CNPase+) and the arrow in (G) (CC1+). At the same time point EYFP+/DCX+ neuroblasts were present in the SEZ, arrows in (H). Scale bars, 50 μm (A, B, D, and E); 20 μm (C, F, G, and H). The dashed line in (B) and (C) indicates the wall of the lateral ventricle (LV).