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Replication and lethality of the CK/1180 and CK/1214 viruses in mice. (A and B) Six-week-old SPF BALB/c mice (three/group) were inoculated intranasally with 106 EID50 of each virus, and organs were collected on day 3 postinfection for virus titration in eggs. Data are means ± standard deviations (SD). (C to F) Mortality assessment of mice infected with different H5N1 viruses: CK/1180 (C), CK/1214 (D), R-CK/1180 (E), and R-CK/1214 (F).
