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. 2016 Dec 16;37(2):729–736. doi: 10.3892/or.2016.5327

Figure 4.

Figure 4.

The effects of berberine and/or caspase-1 inhibitor on the mRNA expression level of caspase-1 and IL-1β. After administration of berberine (80 µM) and/or caspase-1 inhibitor for 48 h, the mRNA expression level was detected by real-time PCR. (A) Caspase-1 mRNA expression in the Saos-2 osteosarcoma cells. (B) Caspase-1 mRNA expression in the MG-63 osteosarcoma cells. (C) IL-1β mRNA expression in the Saos-2 osteosarcoma cells. (D) IL-1β mRNA expression in the MG-63 osteosarcoma cells. GAPDH served as an internal control. Data are expressed as mean ± SEM. n=3. *P<0.05 vs. control, **P<0.01 vs. control. #P<0.05 vs. berberine group.