Figure 2.

LL-37 increases the migration and invasion of MM cells. The relative migration of (A) A375 and (B) A875 cells, and the relative invasion of (C) A375 and (D) A875 cells following exposure to 0, 0.05, 0.5 and 5 µg/ml LL-37 for 12 and 24 h, respectively, as determined using Transwell assays (magnification, ×200). Data represent the mean ± standard deviation of three randomly selected fields of view. *P<0.05 vs. 0 µg/ml LL-37. LL-37, cathelicidin antimicrobial peptide; MM, malignant melanoma.