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. 2016 Nov 1;14(6):5171–5179. doi: 10.3892/mmr.2016.5913

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Copyright: © Li et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — Representative immunohistochemical staining of NRF2 in laryngeal squamous cell carcinoma and adjacent normal mucosa. Top images exhibit (A) strong and (B) positive expression of NRF2, which is primarily located in cancer cell nuclei. The bottom images exhibit negative NRF2 expression in (C) laryngeal cancer and (D) pericarcinomatous tissues. Positive nuclear NRF2 was defined as a score ≥0.1 (magnification, ×40). NRF2, nuclear factor (erythroid-derived 2)-like 2.