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. 2016 Nov 1;14(6):5171–5179. doi: 10.3892/mmr.2016.5913

Figure 2.

Figure 2.

Representative immunohistochemical staining of KEAP1 in laryngeal squamous cell carcinoma and adjacent normal mucosa. The top two images exhibit (A) strong and (B) positive expression of KEAP1 in the cancer cell cytoplasm. The bottom two images exhibit negative KEAP1 expression in (C) laryngeal cancer and (D) pericarcinomatous tissues. Normal mucosa produced almost no positive KEAP1 expression. Positive cytoplasmic KEAP1 was defined as a score ≥0.5. KEAP1, kelch-like ECH-associated protein-1.