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. 2016 Nov 24;37(1):41–47. doi: 10.3892/or.2016.5274

Table I.

Shared CNAs between STUMP (upper value) and sarcoma (bottom value).

Chr Cytoband AvgCGHLR Gene names
  1 p22.2-p22.1 3.37 TGFBR3
3.39
  2 q32.2 3.25 COL5A2
2.95
12 q24.11 2.82 SART3, ISCU, TMEM119,
2 SELPLG, CORO1C, SSH1
13 q32.1 2.51 UGCGL2
1.51
19 q13.43 3.64 CHMP2A, UBE2M,
1.98 LOC100131691, MZF1
21 q22.3 3.94 C2CD2, ZNF295
2.02
22 q12.1 2.26 PITPNB
2.21
X q28 1.46 ARHGAP4, ARD1A,
1.35 RENBP, HCFC1

TGFBR3: decreased expression of this receptor has been observed in various cancers (57). COL5A2: colorectal carcinogenesis is associated with stromal expression of COL11A1 and COL5A2 (20). SART3: an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy (www.genecards.org). CORO1C: silencing of CORO1C gene expression inhibited cancer cell proliferation, migration and invasion (10). SSH1: plays a role in cancer cell motility and invasion. Amplification reported in testicular germ cell tumor (21,22). CHMP2A: diseases associated include osteosarcoma, and adenocarcinoma (www.genecards.org). MZF1: significantly induces tumor formation and liver metastasis, furthermore, MZF1 expression is positively correlated with Axl expression in resected colorectal cancer. Diseases associated also include bladder TCC (www.genecards.org) (23).