Figure 3.

Effects of midazolam on cell survival signaling in oxidative stress-induced cortical neuronal cells. Cells were treated with the indicated reagents at the specified doses for 24 h and western blotting was performed and semi-quantified. *P<0.05 vs. control; **P<0.05 vs. the BSO/H₂O₂-treated cells. BSO, buthionine sulfoximine; H₂O₂, hydrogen peroxide; MDZ, midazolam; p, phosphorylated; ERK1/2, extracellular signal-regulated kinases 1/2; JNK, c-Jun N-terminal kinases; NF-κB, nuclear factor-κB; PKC-ε, protein kinase C-ε.