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Release of both (A) matrix metalloproteinase (MMP)-9 and (B) nuclear factor-κB (NF-κB) p65 activity in melanoma with or without BRAFV600E mutation. *P<0.05 compared to DHMEQ-treated cells; **P<0.05 compared to osteopontin (OPN) + DHMEQ-treated cells. OPN, osteopontin; OD, optical density; PBMCs, peripheral blood mononuclear cells.
