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Acceptance of alkyne-modified NAD+ analogues 1–4 by different ARTDs without or with competition of natural substrate.a
= analogue is well processed, 
= analogue is processed with lower efficiency, 
= analogue is not processed.
| NAD+ analogue | Nat. NAD+ | ARTD1 | ARTD2 | ARTD5 | ARTD6 |
| 1 | – | |
|
|
|
| 1:1 | |
|
|
|
|
| 2 | – | |
|
|
|
| 1:1 | |
|
|
|
|
| 3 | – | |
|
|
|
| 1:1 | |
|
|
|
|
| 4 | – | |
|
|
|
| 1:1 | |
|
|
|
|
aAll gels are depicted in Supporting Information File 1, Figure S1 and Figure S2.
