Table 2. Multivariable covariate-adjusted hazard ratios for all cause and lung cancer specific mortality.
Patient Characteristics | All Cause HRa (95% CIb) | All Cause P-value | Lung Cancer-specific HRa (95% CIb) | Lung Cancer-specific P-value |
---|---|---|---|---|
Prior cancer diagnosis (vs None) | ||||
Yes (any) | 1.01 (0.98–1.04) | 0.523 | 0.79 (0.76–0.82) | <0.001 |
Age (years; vs 66–74) | ||||
75–85 | 1.36 (1.33–1.40) | <0.001 | 1.30 (1.26–1.34) | <0.001 |
>85 | 1.85 (1.77–1.94) | <0.001 | 1.71 (1.61–1.81) | <0.001 |
Sex (vs female) | ||||
Male | 1.30 (1.27–1.34) | <0.001 | 1.27 (1.22–1.31) | <0.001 |
Race/ethnicity (vs white) | ||||
Black | 0.92 (0.87–0.96) | 0.001 | 0.91 (0.86–0.97) | 0.005 |
Hispanic | 0.86 (0.76–0.99) | 0.029 | 0.89 (0.76–1.05) | 0.175 |
Other | 0.82 (0.76–0.87) | <0.001 | 0.85 (0.78–0.92) | <0.001 |
Marital Status (vs married) | ||||
Sep/Div/Widc | 1.13 (1.10–1.16) | <0.001 | 1.12 (1.08–1.16) | <0.001 |
Single | 1.12 (1.06–1.18) | <0.001 | 1.14 (1.06–1.21) | <0.001 |
Unknown | 1.16 (1.08–1.24) | <0.001 | 1.11 (1.02–1.22) | 0.018 |
Histology (vs other non-small cell lung cancer [NSCLC]) | ||||
Small Cell | 1.25 (1.17–1.33) | <0.001 | 1.38 (1.28–1.48) | <0.001 |
Adenocarcinoma | 0. 70 (0.67–0.72) | <0.001 | 0.70 (0.67–0.73) | <0.001 |
Squamous | 0.89 (0.86–0.92) | <0.001 | 0.91 (0.87–0.95) | 0.071 |
Comorbidity (vs none) | ||||
One | 1.25 (1.21–1.29) | <0.001 | 1.06 (1.04–1.09) | <0.001 |
Two or more | 1.56 (1.52–1.61) | <0.001 | 1.35 (1.29–1.40) | <0.001 |
Rule out | 0.95 (0.89–1.02 | 0.148 | 0.96 (0.89–1.04) | 0.337 |
Payer Status (vs no) | ||||
Medicaid | 1.26 (1.21–1.30) | <0.0011 | 1.23 (1.12–1.35) | <0.001 |
Treatment Status (vs no Treatment) | ||||
Surgery only | 0.39 (0.38–0.41) | <0.001 | 0.33 (0.31–0.34) | <0.001 |
Chemotherapy only | 1.04 (0.96–1.12) | 0.376 | 1.23 (1.12–1.35) | <0.001 |
Radiation only | 0.88 (0.84–0.92) | <0.001 | 0.94 (0.89–0.99) | 0.017 |
Two or more | 0.69 (0.67–0.72) | <0.001 | 0.77 (0.74–0.81) | <0.001 |
HR denotes hazard ratio of all cause and lung cancer specific death for the above covariates.
CI denotes confidence interval.
Separated/Divorced/Widowed.