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. 2017 Jan 31;116(6):793–801. doi: 10.1038/bjc.2017.9

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Copyright © 2017 Cancer Research UK

From twelve months after its original publication, this work is licensed under the Creative Commons Attribution-NonCommercial-Share Alike 4.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/4.0/

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(A) Dot plots represent LINE-1 and L1-MET methylation percentages in adenomas of single MAP, (B) FAP/AFAP and (C) sporadic patients; black dots identify adenomas and red dots indicate KRAS/NRAS p.G12C-mutated polyps; the green line symbolises the methylation threshold (60%) for LINE-1 and L1-MET assays; bars show the mean values of LINE-1 or L1-MET methylation percentages among adenomas of the same patient and light blue asterisks show the methylation level of the corresponding carcinomas; symbols and colours are reported as per the legend below. WT, wild type. A full color version of this figure is available at the British Journal of Cancer journal online.