Table 1. Summary of the compounds presented in this paper, their affinity towards CK2α and PDB accession codes for the corresponding crystal structures. (n.d. = not determined, n.b. = not binding).
Structure | K d (μM) | PDB | |
1 | n.d. | 5CLP | |
2 | n.d. | 5CVF | |
3 | 630 | 5CS6 | |
4 | 270 | 5CSH | |
5 | 58 | 5CSP | |
6 | n.d. | 5CSV | |
CAM4066 (7) | 0.320 | 5CU3/; 5CU4 | |
Pro-CAM4066 (8) | n.d |