Skip to main content
. 2017 Mar 17;7:44754. doi: 10.1038/srep44754

Figure 6. PFD inhibits TNF-α-induced apoptosis in primary hepatocytes with reduced caspase-8 and -3 activities.

Figure 6

(a) Representative images of the primary hepatocytes from WT mice pretreated with or without PFD (1000 μM) followed by vehicle (Veh), or D-galactosamine and TNF-α (GalN/TNF) treatment for 16 h. (b) Representative western blots and (c) caspase-8 activities of primary hepatocytes pretreated with or without indicated concentrations of PFD followed by GalN/TNF treatment for 16 h. TNF-R1: tumor necrosis factor receptor 1, cFLIP: cellular FADD-like IL-1β-converting enzyme-inhibitory protein. **p < 0.01. n = 6–8.