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. 2017 Mar 16;10:7. doi: 10.1186/s13039-017-0309-5

Fig. 3.

Fig. 3

Comparison of the standard diagnostic approach and array-CGH in WDLPS, DDLPS and MLPS tumors. On the left the conventional karyotyping and/or FISH results are shown. Black arrows depict the supernumerary ring chromosomes in WDLPS and DDLPS tumors (ab) and the balanced translocation t(12;16) in MLPS sample (c). DDIT3 break apart probe was used in FISH analysis (one orange and one green signal pattern indicate a rearrangement of the DDIT3 gene region). On the right the overview of all copy number aberrations (CNAs) detected by array-CGH is presented. Red and blue colors represent losses and gains, respectively