Table 2.
Cumulate incidence and hazard ratio, crude and adjusted, for hospitalization or death, with respect to socio demographic characteristics, clinical profile, and treatment received for heart failure
| Cumulate Incidence | Crude Hazard Ratio | Adjusted Hazard Ratio | ||||
|---|---|---|---|---|---|---|
| Rate (%) | 95% Confidence interval | HR | 95% Confidence interval | HR | 95% Confidence interval | |
| Goblal incidence | 37.6 | 36.5-38.7 | ||||
| Ejection Fraction | ||||||
| Ejection Fraction>50 | 17.0 | 13.3-20.7 | 1 | 1 | ||
| Ejection Fraction <=50 | 27.3 | 22.1-32.4 | 1.81 | 1.31-2.49 | 1.36 | 0.99-1.88 |
| Missing Ejection Fraction | 39.1 | 38.0-40.2 | 2.33 | 1.84-2.95 | 1.84 | 1.45-2.33 |
| Previous hospitalization for heart failure | 51.3 | 49.5-53.1 | 2.18 | 2.03-2.34 | 1.81 | 1.68-1.95 |
| Gender (Male) | 39.8 | 38.2-41.4 | 1.15 | 1.07-1.23 | 1.24 | 1.14-1.34 |
| Age (quintiles) | ||||||
| (<=71 years; reference | 29.0 | 26.8-31.1 | 1 | 1 | ||
| 72 - 78 | 33.3 | 31.2-35.5 | 1.14 | 1.02-1.28 | 1.03 | 0.91-1.16 |
| 79 - 82 | 38.1 | 35.6-40.5 | 1.43 | 1.27-1.61 | 1.21 | 1.07-1.37 |
| 3 - 86 | 41.1 | 38.5-43.6 | 1.62 | 1.44-1.82 | 1.30 | 1.14-1.48 |
| >=87 | 48.8 | 46.2-51.3 | 2.17 | 1.94-2.43 | 1.60 | 1.40-1.83 |
| Socio economic deprivation index | ||||||
| 1 (less disadvantaged) | 33.5 | 31.1-35.8 | 1 | 1 | ||
| 2 | 36.7 | 34.3-39.1 | 1.08 | 0.96-1.21 | 1.10 | 0.98-1.24 |
| 3 | 37.3 | 34.9-39.6 | 1.06 | 0.95-1.19 | 1.01 | 0.90-1.13 |
| 4 | 38.6 | 36.2-41.0 | 1.11 | 0.99-1.25 | 1.03 | 0.92-1.16 |
| 5 (more disadvantaged) | 42.8 | 40.4-45.3 | 1.28 | 1.14-1.43 | 1.13 | 1.01-1.27 |
| Patients requiring home care | 57.0 | 55.0-59.1 | 2.13 | 1.98-2.29 | 1.58 | 1.46-1.71 |
| Cardiovascular risk factors | ||||||
| Hypertension | 38.3 | 37.1-39.5 | 1.13 | 1.04-1.22 | 1.08 | 0.99-1.19 |
| Diabetes | 41.6 | 39.7-43.5 | 1.25 | 1.16-1.34 | 1.17 | 1.08-1.26 |
| Hypercholesterolemia | 34.5 | 32.6-36.4 | 0.90 | 0.83-0.97 | 0.94 | 0.86-1.02 |
| Obesity | 37.7 | 35.5-40.0 | 0.99 | 0.91-1.08 | 1.00 | 0.92-1.10 |
| Smoking habit | 39.2 | 35.5-43.0 | 0.98 | 0.87-1.11 | 1.04 | 0.91-1.19 |
| Cardiovascular diseases | ||||||
| Coronary heart disease | 41.5 | 39.4-43.6 | 1.21 | 1.12-1.31 | 1.11 | 1.02-1.21 |
| Atrial fibrillation | 42.4 | 40.6-44.2 | 1.31 | 1.22-1.41 | 1.05 | 0.96-1.15 |
| Stroke | 44.7 | 41.2-48.1 | 1.41 | 1.26-1.57 | 1.15 | 1.03-1.29 |
| Peripheral artery disease | 45.4 | 41.0-49.8 | 1.45 | 1.27-1.66 | 1.11 | 0.97-1.28 |
| Other comorbidities | ||||||
| Chronic obstructive pulmonary disease | 45.1 | 42.3-47.8 | 1.39 | 1.28-1.52 | 1.25 | 1.14-1.37 |
| Chronic renal failure | 44.8 | 42.3-47.4 | 1.47 | 1.35-1.60 | 1.18 | 1.08-1.29 |
| Drug therapy | ||||||
| ACE inhibitor or ARB* | 37.3 | 36.1-38.5 | 0.91 | 0.84-0.99 | 0.85 | 0.78-0.93 |
| Beta-blocker | 37.9 | 35.3-40.5 | 1.00 | 0.91-1.09 | 1.03 | 0.94-1.14 |
| Loop diuretics | 42.5 | 41.3-43.8 | 2.27 | 2.05-2.51 | 1.64 | 1.48-1.82 |
| Statins | 35.1 | 33.6-36.6 | 0.87 | 0.81-0.94 | 0.85 | 0.79-0.93 |
a ACE angiotensin converting enzyme, ARB Angiotensin Receptor Blocker