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. 2017 Mar 16;18:237. doi: 10.1186/s12864-017-3608-7

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Sex biased gene expession through development. a - c: Shotgun plots for comparisons of females and males at 1, 2, and 4 months of age. In each plot the number of total differentially expressed genes is shown in the upper right corner and the number of up-regulated vs down-regulated transcripts is shown with an up or down arrow. Log2 fold changes were calculated by taking the log (base2) of the quotient of mean counts in female animals (numerator) and male animals (denominator). d: Venn diagram of sex-biased transcript expression at 1, 2, and 4 months of age. e GO enrichment treemap for transcripts with sex-biased expression at 4 months of age