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. 2017 Mar 17;7:44653. doi: 10.1038/srep44653

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Copyright © 2017, The Author(s)

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Boxplots depicting RNA levels of 16 genes in the FLC mRNA signature in FLC (n = 6), HCC (n = 263), CCA (n = 36), non-malignant liver (NML, n = 50), and non-malignant cholangiocyte/bile duct (NMC, n = 9) from TCGA. Y-axis shows counts normalized by DESeq. Shaded regions of boxplots show the 25^th–75^th quantiles of the data with the median denoted by a bold line. Whiskers of boxplots represent data <25^th and >75^th quantiles. Circles represent data points that are outliers, defined as points <25^th quantile minus 1.5*IQR (interquartile range, 75^th–25^th quantile) or >75^th quantile plus 1.5*IQR. *FDR < 0.05 (DESeq, negative binomial test) of FLC compared to both HCC and CCA.