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. 2017 Mar 16;17:201. doi: 10.1186/s12885-017-3187-7

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — YBX1 silencing in Hs578T cells inhibited cell migration but not cell invasion. a-b Knockdown of YBX1 in Hs578T breast cancer cells decreased gene level and protein expression of YB-1. c-d YBX1 silenced cells showed a a concomitant reduction in cell migration and a downward trend for cell invasion. Error bar = SEM, ** p < 0.01, ***p < 0.001. Representative fields of the migration and invasion assay at 10X magnification are shown as well (Scale bar =100 μm)