Table 2. Tick-borne encephalitis (TBE) virus diagnostic test results, TBE case, the Netherlands, June 2016.
Material | CSF | Serum | Serum | Urine | |
---|---|---|---|---|---|
Date (2016) | 15 July | 15 July | 8 August | 8 August | |
RIVM |
Serology (ELISA) |
IgM borderline positive OD 450 0.421 |
IgM positive 355 VIEU/mL |
IgM positive 341 VIEU/mL |
NA |
IgG positive OD 450 3.064 |
IgG positive > 650 VIEU/mL |
IgG positive > 650 VIEU/mL |
|||
PCR | Negative | ND | ND | Negative | |
Medical University, Vienna |
Serology (ELISA) |
ND |
IgM positive | IgM positive | NA |
IgG positive > 1,000 VIEU/mL |
IgG positive 50,600 VIEU/mL |
||||
Virus neutralisation assay | ND | Positive titre: 1:10 | Positive titre: 1:480 | NA |
CSF: cerebrospinal fluid; NA: not applicable; ND: not done; OD450 Optical density at 450 nm (IgM norm: <0.360 (negative); IgG norm: <0.270 (negative); RIVM: Rijksinstituut voor Volksgezondheid en Milieu (National Institute for Public Health and the Environment); VIEU: Vienna Units.