Table 4.
Examination of Predictive Factors Related to Antimicrobial Prophylaxis Compliance.a
| Predictive Factor | Univariate Odds Ratio (95% confidence interval) | P-value | Multivariate Odds Ratio (95% confidence interval) | P-value |
|---|---|---|---|---|
| Time period | <0.001 | <0.001 | ||
| 2009–2010 | Reference | Reference | ||
| 2010–2014 | 0.37 (0.33–0.42) | 0.40 (0.35–0.45) | ||
| Intensive care unit admission at LRMC | 1.92 (1.70–2.17) | <0.001 | 1.51 (1.27–1.81) | <0.001 |
| Age at injury | 0.99 (0.98–1.00) | 0.032 | – | |
| Blood product requirements 24 hours post-injury | 0.509 | |||
| 1–9 units | Reference | – | ||
| 10–20 units | 0.98 (0.75–1.27) | – | ||
| >20 units | 1.17 (0.88–1.55) | – | ||
| Shock indexb | <0.001 | |||
| 0–1 | Reference | – | ||
| 1–1.5 | 1.46 (1.19–1.79) | – | ||
| >1.5 | 1.77 (1.28–2.46) | – | ||
| Injury severity scorec | <0.001 | <0.001 | ||
| 0–9 | Reference | Reference | ||
| 10–15 | 1.87 (1.59–2.20) | 1.66 (1.38–1.98) | ||
| 16–25 | 1.71 (1.45–2.03) | 1.32 (1.08–1.62) | ||
| ≥26 | 2.40 (2.07–2.79) | 1.68 (1.36–2.08) |
LRMC = Landstuhl Regional Medical Center
a
Using injury severity as a predictor, statistical power is 0.547
b
Shock index is defined as heart rate/systolic blood pressure.
c
Injury severity score is an overall score of severity based on anatomical regional values.28