. 2017 Mar 15;5:e3078. doi: 10.7717/peerj.3078

Table 4. KEGG enrichment of dysregulated DEGs in RA.

KEGG ID	KEGG terms	FDR	Genes
hsa04360	Axon guidance	0.010565	DCC, SEMA6A, SEMA4D, PLXNA2, RGS3, NFAT5, CDK5, UNC5C
hsa03013	RNA transport	0.015948	EIF5B, SAP18, GEMIN4, PABPC1, THOC2, EIF1B, EIF3E
hsa00982	Drug metabolism - cytochrome P450	0.017355	ALDH1A3, CYP1A2, CYP3A5, MGST3, UGT2B15
hsa00980	Metabolism of xenobiotics by cytochrome P450	0.017377	ALDH1A3, CYP1A2, CYP3A5, MGST3, UGT2B15
hsa05200	Pathways in cancer	0.018693	PPARD, PIAS2, DCC, E2F3, PTEN, PDGFA, CSF1R, MAPK8, PIAS1, BRCA2, CEBPA
hsa03040	Spliceosome	0.020842	DHX15, HNRNPA1, DHX16, THOC2, PRPF3, HNRNPU, SRSF5
hsa04910	Insulin signaling pathway	0.021514	RPS6KB1, MAPK8, MKNK2, TSC1, PHKA1, PRKAG1, PPP1CB
hsa05016	Huntington’s disease	0.021575	POLR2J, NDUFA2, UQCRC1, TGM2, BBC3, NDUFA7, GRIN1, ATP5O
hsa05010	Alzheimer’s disease	0.023516	NDUFA2, UQCRC1, CAPN2, NDUFA7, GRIN1, ATP5O, CDK5
hsa04141	Protein processing in endoplasmic reticulum	0.024488	SEC63, P4HB, SAR1A, CAPN2, MAPK8, AMFR, HERPUD1
hsa03060	Protein export	0.02558	SRP54, SEC63, SEC11A
hsa04010	MAPK signaling pathway	0.026502	MAPK8IP2, PDGFA, RRAS, MAPK8, MAP3K11, MKNK2, DUSP3, STK3, CACNB2, MAP3K8
hsa03440	Homologous recombination	0.031046	RPA2, RPA3, BRCA2
hsa05160	Hepatitis C	0.033309	PIAS2, MAPK8, PIAS1, IFNA21, IRF9, EIF3E

Notes.

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