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. 2016 Jul 23;7(42):68033–68043. doi: 10.18632/oncotarget.10797

Figure 2. Densities of tumor associated macrophages in LGSOC and HGSOC tissue specimens.

Figure 2

(A) Representative pictures for immunohistochemical staining of CD68+ macrophages in clinical samples of LGSOC and HGSOC. Magnification 20× and 40×. Scatter plot shows all data points and mean ± SEM for the entire set of patients (n = 25 and n = 55, for LGSOCs and HGSOCs respectively, ***p < 0.0001). Bar graphs depict data (mean ± SEM) following stratification per stage (Early stage, n = 10 and n = 8; Advanced Stage n = 15 and n = 47, for LGSOCs and HGSOCs respectively, ***p < 0.0001). (B) Representative pictures for immunohistochemical staining of CD163+ macrophages in clinical samples of LGSOC and HGSOC. Magnification 20× and 40×. Scatter plot shows all data points and mean ± SEM for the entire set of patients (see above for sample sizes, ***p < 0.0001). Bar graphs depict data (mean ± SEM) following stratification per stage (see above for sample sizes, ***p < 0.0001). (C) Bar charts showing the CD163/CD68 ratio (mean ± SEM) in the entire population (see above for sample sizes, *p = 0.02) and after stratification per stage (see above for sample sizes, *p = 0.049).