Table 1. Correlations between GOLPH3 expression and clinicopathological parameters.
Clinicopathological parameters | Cases (n = 148) | GOLPH3 expression | P value | |
---|---|---|---|---|
Low (71) | High (77) | |||
Gender | ||||
Male | 89 | 41 | 48 | 0.569 |
Female | 59 | 30 | 29 | |
Age (years) | ||||
< 65 | 67 | 35 | 32 | 0.345 |
≥ 65 | 81 | 36 | 45 | |
Histology | ||||
Differentiated | 82 | 47 | 35 | 0.011 |
Undifferentiated | 66 | 24 | 42 | |
Distance from anal verge(cm) | ||||
< 6 | 57 | 29 | 28 | 0.576 |
≥ 6 | 91 | 42 | 49 | |
CEA(ng/ml) | ||||
< 3.4 | 70 | 41 | 29 | 0.014 |
≥ 3.4 | 78 | 30 | 48 | |
Clinical Tumor status | ||||
cT3 | 80 | 45 | 35 | 0.029 |
cT4 | 68 | 26 | 42 | |
Clinical Node status | ||||
cN0 | 54 | 32 | 22 | 0.037 |
cN+ | 94 | 39 | 55 | |
Recurrence | ||||
Negative | 105 | 59 | 46 | 0.002 |
Positive | 43 | 12 | 31 | |
Distant metastasis | ||||
Negative | 122 | 64 | 58 | 0.018 |
Positive | 26 | 7 | 19 |
Abbreviations: GOLPH3, Golgi phosphoprotein 3; CEA, carcinoembryonic antigen.