Table 3. Multivariate analysis for tumor response of nCRT in LARC.
| Parameters | Odds ratio | 95% Confidence interval | P value |
|---|---|---|---|
| Good response | |||
| CEA | 1.871 | 0.834–3.981 | 0.182 |
| cT | 2.762 | 1.112–6.356 | 0.039 |
| cN | 2.654 | 1.136–6.524 | 0.034 |
| GOLPH3 | 3.952 | 1.655–10.327 | 0.026 |
| Down staging | |||
| CEA | 1.961 | 0.864–4.125 | 0.352 |
| cT | 2.638 | 1.109–6.356 | 0.029 |
| cN | 2.456 | 1.694–5.324 | 0.037 |
| GOLPH3 | 2.951 | 1.523–11.324 | 0.021 |
Abbreviations: nCRT, neoadjuvant chemoradiotherapy; LARC, locally advanced rectal cancer ; cT, clinical Tumor status; cN, clinical Node status; CEA, carcinoembryonic antigen; GOLPH3, Golgi phosphoprotein 3.