Figure 6. Response to chemotherapeutic drugs.
The effects of Vincristine A. Taxol B. Irinotecan C. Doxorubicin D. Ifosfamide E. 5-Fluorouracile F. Mitoxantrone G. and Cisplatin H. were assessed for 231 and LT cells. IC50 [μM] values are shown. LT cells showed a significantly increased sensitivity to Vincristine and Irinotecan (response index 0.06 and 0.58, respectively) and were more resistant to Ifosfamide (RI=2.38). LT cells also show a slightly reduced sensitivity to 5-Fluorouracile as compared to 231 cells. No significant differences were observed for the other drugs.