Table 1. Growth-related genes (top 10) expression analysis of MDA-MB-231 vs. MCF-7 mined from the NCBI database (GSE34987).
| Gene name | Fold increase in MDA-MB-231 vs. MCF-7 (mean ± SEM) |
|---|---|
| GPR116 | 2.05 ± 0.00 |
| EMP1 | 1.92 ± 2.00 |
| ADORA2B | 1.64 ± 1.00 |
| PDGFC | 1.61 ± 1.00 |
| EGFR | 1.55 ± 1.00 |
| CSF1R | 1.54 ± 0.00 |
| IGF2BP3 | 1.49 ± 0.00 |
| CSF2 | 1.41 ± 0.00 |
| PKIB | 0.65 ± 1.00 |
| GREB1 | 0.60 ± 0.00 |
GPR116: G protein-coupled receptor 116; EMP1: epithelial membrane protein 1; ADORA2B: adenosine A2b receptor; PDGFC: platelet derived growth factor C; EGFR: epidermal growth factor receptor; CSF1R: colony stimulating factor 1 receptor; IGF2BP3: insulin-like growth factor 2 mRNA binding protein 3; CSF2: colony stimulating factor 2 (granulocyte-macrophage); PKIB: protein kinase (cAMP-dependent, catalytic) inhibitor beta; GREB1: growth regulation by estrogen in breast cancer 1.