Table 1. The associations of Hsp60 expression with clinical characteristics of HCC patients.
Variables | No. of cases | Hsp60 expression | P value (χ2 test) | |
---|---|---|---|---|
Low | High | |||
Total | 295 | 120 | 175 | |
Age (years) | 0.620 | |||
<54 | 160 | 63 | 97 | |
≥54 | 135 | 57 | 78 | |
Gender | 0.394 | |||
female | 36 | 17 | 19 | |
male | 259 | 103 | 156 | |
HBsAg | 0.298 | |||
Negative | 23 | 7 | 16 | |
Positive | 272 | 113 | 159 | |
AFP(ng/ml) | 0.020 | |||
<200 | 169 | 59 | 110 | |
≥200 | 126 | 61 | 65 | |
Tumor size(cm) | 0.741 | |||
<5 | 122 | 51 | 71 | |
≥5 | 173 | 69 | 104 | |
Tumor number | 0.596 | |||
Single | 234 | 97 | 137 | |
Multiple | 61 | 23 | 38 | |
Differentiation grade | 0.004 | |||
I+II | 78 | 21 | 57 | |
III+IV | 217 | 99 | 118 | |
TNM stage | 0.680 | |||
I+II | 230 | 95 | 135 | |
III+IV | 65 | 25 | 40 | |
PVTT | 0.361 | |||
No | 262 | 105 | 157 | |
Yes | 33 | 15 | 18 | |
Adjuvant TACE therapy | 0.855 | |||
No | 218 | 88 | 130 | |
Yes | 77 | 32 | 45 | |
Death | 0.742 | |||
No | 186 | 77 | 109 | |
Yes | 109 | 43 | 66 | |
Relapse | 0.450 | |||
No | 108 | 47 | 61 | |
Yes | 287 | 73 | 114 |
AFP, alpha-fetoprotein; HBsAg, hepatitis B virus surface antigen; HCC, hepatocellular carcinoma; Hsp60, heat shock protein 60; PVTT, portal vein tumor thrombus; TACE, transcatheter arterial chemoembolization.