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. 2016 Sep 2;7(42):68990–69001. doi: 10.18632/oncotarget.11837

Figure 4. Higher inflammation in bronchoalveolar lavage fluid of melanoma-treated Mcpt5-Cre+ vs. Mcpt5-Cre− animals.

Figure 4

Melanoma cells (B16.F10) were intravenously injected into Mcpt5-Cre− or Mcpt5-Cre+ littermate mice. After 11 days, bronchoalveolar lavage (BAL) was performed. As controls, BAL fluids from naïve Mcpt5-Cre− and Mcpt5-Cre+ mice were assessed. A-B. Total cell counts (A) and differential counting (B) of BAL fluid from either naïve or melanoma-treated Mcpt5-Cre− or Mcpt5-Cre+ mice. Results are given as mean ± SD; n = 4; * p < 0.05, ** p < 0.01. C. Representative images of May-Grünwald/Giemsa-stained cytospin slides prepared from BAL fluid of melanoma-treated Mcpt5-Cre− or Mcpt5-Cre+ mice. Note the presence of macrophages with ingested melanin (insets). Original magnification = 400 x; Bar = 10 μm.