Table 4. Acute toxicity reactions of the three groups of patients.
| Toxicity reaction | CCRT | CCRT+AC | IMRT alone | P value |
|---|---|---|---|---|
| leukopenia | a | a | <0.001 | |
| 0 | 18 | 4 | 30 | |
| 1 | 20 | 9 | 8 | |
| 2 | 29 | 18 | 3 | |
| 3 | 13 | 9 | 1 | |
| neutropenia | a | a | <0.001 | |
| 0 | 37 | 10 | 39 | |
| 1 | 21 | 11 | 2 | |
| 2 | 17 | 6 | 0 | |
| 3 | 5 | 3 | 1 | |
| anemia | a | a | 0.002 | |
| 0 | 46 | 23 | 37 | |
| 1 | 18 | 14 | 3 | |
| 2 | 14 | 3 | 2 | |
| 3 | 2 | 0 | 0 | |
| thrombocytopenia | 0.093 | |||
| 0 | 68 | 36 | 41 | |
| 1 | 7 | 2 | 1 | |
| 2 | 2 | 2 | 0 | |
| 3 | 3 | 0 | 0 | |
| liver dysfunction | a | a | <0.001 | |
| 0 | 64 | 20 | 39 | |
| 1 | 13 | 16 | 2 | |
| 2 | 3 | 2 | 1 | |
| 3 | 0 | 1 | 0 | |
| renal dysfunction | 0.108 | |||
| 0 | 79 | 38 | 41 | |
| 1 | 10 | 2 | 1 | |
| gastrointestinal | a | a | <0.001 | |
| 0 | 8 | 7 | 33 | |
| 1 | 18 | 5 | 5 | |
| 2 | 47 | 27 | 4 | |
| 3 | 7 | 1 | 0 | |
| weight loss | a | a b | ||
| 0 | 22 | 4 | 25 | <0.001 |
| 1 | 35 | 17 | 10 | |
| 2 | 23 | 18 | 7 | |
| 3 | 0 | 1 | 0 |
a indicated that the difference of the acute toxicity reaction degree between that group and the IMRT alone group was statistically significant (p<0.05), while b meant that the difference of the acute toxicity reaction degree between that group and the CCRT group was statistically significant (p<0.05).