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. 2016 Sep 13;7(42):69087–69096. doi: 10.18632/oncotarget.12011

Table 1. Characteristics of included studies.

No. of Studies Author Year Country Cases (n) Method Antibody Dilution Cut-off Value Positive Percentage
1 Chen[14] 2016 China 101 IHC 1:100 5 score 57.8%
2 Zhang[15] 2016 China 94 IHC NA 10% 53.2%
3 Yang[16] 2015 China 20 ISH - - 55.0%
4 Zheng[17] 2014 China 98 IHC NA 50% 77.6%
5 Qi[18] 2014 China 96 IHC NA 2 score 68.8%
6 Liu[19] 2014 China 65 IHC 1:200 3 score 64.5%
7 Wang[20] 2014 China 121 IHC 1:200 10% 79.3%
8 Yan[21] 2013 China 50 IHC 1:500 3 score 88.0%
9 Feng[22] 2012 China 70 IHC NA 2 score 74.3%
10 Ouyang[23] 2011 China 54 IHC 1:50 10% 61.1%
11 Rong[24] 2006 China 85 IHC 1:150 0% 75.3%
12 Ma[25] 2005 China 32 ISH - - 68.8%

Abbreviations: IHC = immunohistochemistry, ISH= in situ hybridization, NA= not available.