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. 2016 Sep 20;7(51):84575–84586. doi: 10.18632/oncotarget.12144

Figure 1. SHP1 expression in chronic HCV patients.

Figure 1

A. mRNA expression levels of SHP1 in livers and PBMCs from HCV infected patients (the results are represented as mean values ± S.D, **p<0.01). B. Western blot analysis of SHP1 in livers and PBMCs of HCV infected patients. The presented results are obtained by comparing healthy donors (HDs) with HCV infected patients with different viral loads (VLs). Represented experiments are two examples of what happen in the liver and PBMCs of the studied subjects. HD1: Healthy Donor 1, HCV 1: HCV Infected patient 1, HD2: Healthy Donor 2 and HCV2: HCV infected patient 2. C, D, E. Correlation between SHP1 expression in HCV+ livers/PBMCs and plasma ALT, AST levels and Viral Loads (VL), respectively. The Spearman's rho was evaluated with a Bonferroni's correction of 0.000568, (livers: rho values 0.869, *p<0.05; PBMCs: rho values 0.788, *p<0.05).