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A. Mean (± SD) blood concentration of ridaforolimus following oral dosing at 22, 28, and 33 mg/m2 once daily for 5 days per week of a 28-day cycle in pediatric patients. Top panel: linear scale; bottom panel: semi-log scale. B. Exposure (AUC0–24h) relative to actual dose of oral ridaforolimus (calculated based on body surface area) in pediatric patients.
